etaiwannews.com 2003-04-06 / Associated Press / SINGAPORE

Hong Kong and Malaysia reported new deaths from a mystery illness yesterday, bringing the global death toll to at least 89, while China vowed to share more information on the disease that apparently started in one of its southern provinces.

Hong Kong reported three new deaths yesterday and said the number of its people infected with severe acute respiratory syndrome, or SARS, had risen to 800 - accounting for more than a third of the world's more than 2,300 cases. The disease has killed 20 in the territory.

U.S. President George W. Bush followed the lead of governments in Asia and Canada by giving American health authorities the power to quarantine anyone infected with severe acute respiratory syndrome, or SARS.

U.S. health authorities are investigating about 100 suspected cases of the disease at home. More than 2,300 people worldwide have been infected.

The U.S. Pacific Command ordered all military personnel not to travel to China and Hong Kong - including Navy ships that regularly dock in Hong Kong - unless it was essential to their missions.

In China, where the government has been criticized for failing to notify the international community when SARS first hit in November, Vice Premier Wu Yi promised to start releasing more information to the public, the official Xinhua News Agency reported.

Malaysia became the 20th place to join the list of SARS-affected areas after confirming that the illness killed a 64-year-old man who died on March 30 in Kuala Lumpur. He developed SARS symptoms during a recent visit to China, said Malaysia's Health Ministry Director-General Mohamad Taha Arif.

Thailand's Health Minister Sudarat Keyuraphan said he was considering calling military medics to help screen incoming passengers for the disease. The World Health Organization, or WHO, has reported seven SARS cases and two deaths in Thailand.

Singapore said the number of new infections in the city-state was dropping and people should resume their normal routines. The government said it would begin reopening the country's schools in the coming week after shutting them last month due to the disease, which has killed six people and infected 101.

However, parents will have to sign declarations saying their children are healthy, and students who have traveled outside Singapore will have their temperatures taken by school staff for 10 days after their return.

San Petersburg Times By Margaret Wong

THE ASSOCIATED PRESS HONG KONG - Health officials announced a sharp rise Monday in cases of a flu-like disease at a Hong Kong apartment complex and slapped a 10-day quarantine on one building as they scrambled to contain the illness that has killed nearly 60 people worldwide.

The 92 new cases at Amoy Gardens apartments brought the total number infected in the 19-building complex to 213.

The surge in cases led some health officials to fear severe acute respiratory syndrome, or SARS, could be more contagious than had been initially expected.

There is still no known treatment for SARS, which has killed nearly 60 people, with the majority of cases in Hong Kong and China.

Three new deaths were reported Sunday, one each in Hong Kong, Toronto and Singapore. More than 1,600 people have been infected around the world.

A World Health Organization official said Monday that experts believe they can soon identify the virus causing SARS, though finding a cure could take longer.

"I think we can identify the causative agent in quite a short time period. We think probably within a few days, at most a few weeks," said Hitoshi Oshitani, the WHO coordinator for SARs, at a news conference in Manila.

"But this doesn't mean we will find the specific treatment for this disease within the short time period."

The illness has prompted officials in Asian countries to impose long-unused quarantine laws, close schools and impose new health screening on travelers. Canadian officials declared a health emergency.

In Hong Kong, residents at Block E of Amoy Gardens, were ordered to stay in their homes until midnight April 9 or face fines or jail time, while being offered regular medical checkups and three free meals per day.

Hong Kong officials said 107 people from Block E are sick.

Hong Kong's health secretary, Dr. Yeoh Eng-kiong, told a news conference the quarantine was forced by "a very exceptional circumstance."

Yeoh was emotional and initially had trouble speaking to reporters. "We haven't done it before and we hope we won't do it again," he said of the quarantine.

Singapore's health minister, Lim Hng Kiang, said the disease may spread more easily than first believed, with some people found to be more infectious than others.

These people can sicken as many as 40 others, he said.

"We run the risk of a huge new cluster of infected people, which could start a chain reaction," Lim told a news conference Sunday.

Yeoh said Hong Kong officials believe the virus was brought to Amoy Gardens by a man infected at a hospital where many of Hong Kong's victims have fallen ill.

Asked whether SARS was spreading through the air, Yeoh said that couldn't be ruled out.

Officials had said previously the illness, which has killed 13 people in Hong Kong, seemed to spread through close contact and Yeoh said experts still believe the sickness is being transmitted mostly through droplets, when victims sneeze or cough and nearby people are infected.

"No one can rule out this possibility of airborne transmission, because the virus can change so quickly these days," Yeoh said.

Police sealed Block E at Amoy Gardens with metal barricades and tape after the quarantine was ordered in the early hours of the morning .

Speaking to local television and radio stations, one resident said he would bide his time with the Internet and video games. A woman grumbled that jail inmates probably get better treatment.

"They only gave me a loaf of white bread," said the woman, identifying herself to TVB television as Ms. Lam. "Have they thought about our feelings? I haven't been jailed before, but I understand that prisoners even get newspapers to read."

In China, where the disease has killed at least 34 people, people rushed to buy surgical masks and herbal cold remedies as unease rose.

In Canada, another death was reported Sunday to bring the toll there to four. About 100 probable or suspect cases have been reported from the west coast city of Vancouver, British Columbia, to the east coast city of New Brunswick.

Officials have closed two hospitals to new patients, and hundreds of people have been quarantined in their homes.

The World Health Organization recommended that international travelers from Toronto and several Asian cities get screened for symptoms, which include high fever, dry cough and shortness of breath.

The International Ice Hockey Federation canceled the women's world championships scheduled to begin Thursday in Beijing, following numerous other cancellations of concerts, anti-war protests and other events in infected areas.

The federation said the spread of the illness to Beijing from southern China put the players at risk.

Hockey players for Canada, the defending champion, were disappointed but understood.

"You could lose your life going there and just being in contact with somebody," forward Danielle Goyette said. "Life is more important than hockey right now."

Time Asia April 7, 2003 / Vol. 161 No. 13 BY JIM ERICKSON

Asia's killer virus has the region on edge. Jim Erickson looks at the outbreak's medical and economic repercussions

The pathology department at the University of Hong Kong is one of the few places on Earth where you can stare death in the face. In the department's lab, a transmission electron microscope capable of magnifying an image up to 150,000 times is being used to view a never-before-seen virus that researchers now believe has killed at least 55 people worldwide and infected more than 1,500. Illuminated on a green phosphorescent screen by a beam of electrons and viewed through an optical device that resembles an upside-down periscope, the virus—this particular specimen had been taken from a relative of a Chinese doctor who was the first victim to die in Hong Kong on March 4—looks every bit the alien matter that it is. "There are the little buggers," says Dr. John Nicholls, a pathologist at the University of Hong Kong, leaning aside so a TIME reporter could take a look. Magnified 100,000 times, the organisms are fuzzy black balls that fill the screen and look like the burrs that stick to your pants during a hike through the woods. You can just make out the little hooks sticking out of the viral body—telltale characteristics that help classify the pathogens as members of the coronavirus family.

Coronaviruses, so called because of their spiky crown of protein globules, are generally not mortally harmful. They are a pest to livestock and in humans are responsible for more than one-third of common cold cases. But the bugs on Nicholls' slide have, for reasons researchers have just begun to investigate, mutated into something far deadlier: a rogue virus that triggers a killer pneumonia recently labeled Severe Acute Respiratory Syndrome (SARS). Since news of the first SARS cases escaped mainland China a month ago, health authorities around the planet have been in a state of high alert, fearful of a worldwide outbreak of a highly contagious and untreatable disease. Last week the disease continued to go global, affecting more than 15 countries, as infected individuals jetted from hot zones to other parts of the world, passing along their unwelcome baggage through sneezes and coughs. Most worrisome, the disease doesn't look like it will die out anytime soon: Thomas Tsang, consultant in community medicine at Hong Kong's Department of Health, says he expects to see as many as 50 new cases a day over the next few weeks—just in the territory alone. LATEST COVER STORY SARS: How Dangerous Is It?  What Else Is Out There?  Tracking a Deadly Virus April 7, 2003 Issue   IRAQ  Bush: Sticking To His Guns  Strategy: Flawed Assumptions  POW: Taken By Surprise

ASIA  Essay: Anger Against America

ARTS & SOCIETY  Matt Dillon's Cambodian Ghosts

NOTEBOOK  Afghanistan: Still Fighting  China: Must-see CCTV  Kashmir: More Killings

TRAVEL  Singapore: The U.N. of Food  Hong Kong: New Flavors

CNN.com: Top Headlines SARS, which is believed to be a form of atypical pneumonia, has already claimed some high-profile victims, including a World Health Organization (WHO) doctor who came into contact with patients in Hanoi and succumbed on Saturday. Secretive Chinese health-care authorities—the disease is suspected to have first surfaced last November in the southern Chinese province of Guangdong—now admit that the country has far more cases and in more places than previously acknowledged. Last week they put the toll at 806 cases and 34 deaths, a statistic that many mainland doctors say still underplays the disease's real effect. In Canada's Ontario province, where 35 people have been stricken and of whom three have died, access to medical facilities has been severely restricted and officials ordered thousands of people to self-quarantine. In Singapore and Hong Kong, schools were ordered closed and governments invoked quarantine laws not used for decades to isolate those who might be carriers. Nearly 1,700 Singaporeans are now confined to their homes. Explained Hong Kong's Chief Executive Tung Chee-hwa in announcing tougher measures to curb the spread of the disease: "Hong Kong is currently facing its most serious contagious disease threat in 50 years."

Drastic steps are being taken in part because so little is known about SARS. Scientists have only begun to deconstruct the virus' DNA to find out where it originates from, how it kills and, crucially, how to counteract it. According to the WHO, the coronavirus, while it can spread quickly, is actually less contagious than the average influenza virus. But once inside a human host, it can be virulent. The pathogen causes high fever and creates an "inflammatory storm" as the body's immune system attempts to fight it off, says one doctor, causing lung tissue to swell and, in the final, brutal stages, suffocating the host. Nguyen Thi Bich, 44, a nurse at Hanoi's French Hospital, where nearly 60 SARS cases have been traced, contracted the disease and was hospitalized for three weeks. "The fever felt like having red ants in my body," she says. "Sometimes I felt my body was about to explode." She was lucky and recovered. But Bich's friend and colleague, nurse Nguyen Thi Uyen, died of SARS. Although the virus appears to attack indiscriminately, once contracted its effects are generally more harmful in the elderly or those with pre-existing medical conditions. "On a scale of 1 to 10, [the disease] is a 12," says Dr. Sydney Chung, dean of the medical faculty at the Chinese University of Hong Kong. "The outcome is that a significant proportion get very ill and end up on a ventilator."

Hong Kong has the unfortunate distinction of being the epicenter of the SARS outbreak outside of mainland China. The first known case to die outside the mainland was in the territory, and nearly 500 people have contracted the virus since then. Just last week, 310 new cases came to light. Still, that's just a fraction of Hong Kong's 7.3 million population, and in fact, the SARS mortality rate isn't very high—fewer than 4% of those who have contracted the disease so far have died. But the limited death toll belies the much wider impact SARS is having on the city's economy and psyche. Indeed, in Hong Kong there seem to be two contagions at work: one is the virus, which is transmitted when a person comes into contact with pathogen-laden droplets; the other is fear, which has spread swiftly through the community, stoked by sentiment that the territory's beleaguered government hasn't done enough to stem the disease's spread.

Until last week, Hong Kong's health officials had downplayed the threat of the virus to avoid public panic. To ease fears, government officials announced that cases appeared to be confined mainly to the city's Prince of Wales Hospital, which received more than one-quarter of the territory's total infections and where more than 100 health-care workers had contracted the disease in the facility's cramped wards. But on March 23, after Dr. William Ho, chief executive of Hong Kong's Hospital Authority, was admitted to hospital with atypical pneumonia, fear of a major outbreak began to seize the public consciousness as the disease spread beyond the Prince of Wales Hospital. By Saturday, more than 100 residents of a Kowloon housing estate had come down with SARS. A branch of the Bank of East Asia was shut down when an employee contracted the disease. The Central Library was closed. On March 28 alone, 58 new cases were confirmed.

Hong Kong now looks like a city under threat of biological-weapons attack. Almost overnight the streets have filled with people wearing surgical and industrial face masks, as if shopping malls and subway stations had suddenly morphed into vast hospital wards. Convenience-store clerks, shopkeepers, bus drivers and even TV talk-show hosts are wearing masks, the latter while on camera. Doctors say the devices can hamper the spread of the disease by corralling coughs and sneezes and by preventing people from touching their noses and mouths. Even transit companies and political parties are handing masks out on the street by the thousands, helping calm citizens who are searching for any incremental advantage over this little-known stalker. Naturally, in this most economically minded of cities, street hawkers are price gouging, charging several dollars each for tissue-thin masks sporting pirated cartoon characters such as Pokémon and Hello Kitty. "Forget about Scud missiles and smart bombs, we could all die if someone with the disease merely coughs," Shirley Li, a Hong Kong resident, told Reuters when explaining why she makes her son wear a mask in public.

The hot-zone atmosphere has unsettled natives and expatriates. Keesler Cronin was already jumpy when she recently took her nine-year-old son to a doctor because he had a sore throat. "Everyone in the office had masks when we got there," Cronin says. But that scene wasn't as bad as what the doctor had to say: "He said, 'If you have the means to leave Hong Kong, I would pack your family and get out of here for a month.' It put the fear of God in me." At Yiu Him House, an apartment complex in northern Hong Kong where several people have been diagnosed with SARS, cleaners last week scrubbed down staircases, elevators and lobbies with disinfectant. A resident who identifies herself only as Mrs. Man eagerly discussed Hong Kong's hottest conversational topic—the different kinds of masks and their prices. "It's good that they're cleaning the building more," she said through a thin paper mask. "One night I saw that they hadn't cleared the garbage, and the next day some people here got atypical pneumonia. You can't be too scared. I'm quite scared, but there's nothing I can do."

Visitors, too, are feeling jittery. "I usually shake hands with everyone when I meet them," says Raynald Denis, a fashion retailer from Montreal who was in Hong Kong and the mainland on business last week. "But on this trip I tried to minimize all contact." Although Hong Kong has not been declared off-limits by the WHO, some governments have issued travel advisories cautioning against visiting destinations with known SARS cases. The Canadian government said it might ban flights to Hong Kong, Singapore and Hanoi if the situation worsens. The Rolling Stones rock band canceled their much-anticipated pair of concerts in Hong Kong. Another major local event, the Hong Kong Rugby Sevens, went ahead but without teams from Italy, France and Argentina, which all stayed home because of the SARS outbreak.

Citizens of overcrowded Hong Kong were hypersensitized to the threats of a rogue virus long before AIDS or the movie Outbreak. The regional transportation hub and trading entrepôt borders Guangdong province and has long been associated with the outbreak of new diseases. The city even has a disease named for it—the Hong Kong flu, which killed 700,000 people globally from 1968-1969, infecting 30% of the world's population in less than nine months. Since 1997, local health authorities also have been periodically quelling eruptions of the avian flu, which is one of the few deadly diseases thought to directly jump from birds to humans. No surprise, then, that Hong Kong's vigilant residents were calling for a comprehensive battle plan against SARS long before their bureaucrats belatedly announced their anti-SARS blueprint on March 27. Parents who have school-age children and local lawmakers accused the government of being complacent and keeping silent about SARS to protect the already fragile economy. But Selina Chow, a legislator and chairman of the Hong Kong Tourism Board, maintains that officials have had to be careful not to start a panic. "We are not just dealing with the scientific containment, we're also dealing with the psychological effect," she says. The decision last Thursday to close local schools for a week and monitor 1,080 people who had close contact with SARS victims "is not due to a scientific need but rather is a move to calm the worries of parents. It's come to a point where, strictly speaking, some of the measures are not for medical reasons."

Still, Hong Kong's health precautions have stopped short of those of ultra-cautious Singapore. There, nearly 1,700 people have been quarantined—they can't leave their homes, and if they do they may be fined up to $5,650. Teacher Melanie Young, who may have been exposed to SARS by a five-year-old student, was cooking dinner for her husband and two children on March 24 when officials from Singapore's Ministry of Health knocked on her door. They delivered quarantine papers stipulating that she and her kids could not venture outside under any circumstances—not even to buy groceries—for 10 days. During that time she was to check the family's temperature daily and "observe good hygiene." It was the first time Singapore had ever invoked its Infectious Disease Act. "I was surprised but I accepted this," Young says. "I take this seriously, especially when it comes to my children." Indeed, precautions are being taken everywhere. The body of Simon Loh, a Singaporean pastor who died from SARS on March 26, was double-bagged and the casket was hermetically sealed before his cremation. At the 39-year-old's funeral, the first five rows closest to the coffin were empty. The pallbearers wore rubber gloves.

In Hong Kong the economic toll of the outbreak is rising, despite the efforts of government spin doctors. Some 300 Hong Kong workers for U.S. computer maker Hewlett-Packard were sent home last week after an employee came down with SARS. Two important economic sectors—tourism and retail—are expected to be hit hard, hurting an economy already wounded by prolonged deflation and by the effects of the Iraq war. According to investment bank Morgan Stanley, Hong Kong could lose $256 million in tourism revenue over the next two months. Local tour guide Carmen Li hasn't gone to her office for four days—most of her bookings have been canceled, as tourists stay clear of the infected territory.

Potentially more dangerous is the impact on local spending. The city's usually crowded haunts—malls, karaoke bars, movie theaters, nightclubs and restaurants—are eerily devoid of traffic. Tommy Cheung, a lawmaker who represents Hong Kong's restaurant industry, says there has been a 10-15% drop in the local dinner business recently. Yu Pang-chun, chairman of the Hong Kong Retail Management Association, reported last week that sales among his association members were down more than 10% compared with the same period last year. That translates into a $50 million-a-week loss in revenue for the city's retailers. The outbreak "is going to have a much greater impact on psychology and consumer confidence than the chicken flu," says Tai Hui, an economist at Standard Chartered Bank. Overall the SARS effect could cut Hong Kong's GDP growth by 0.4 percentage points this year, according to Deutsche Bank economists.

Business owners are trying to cope. "We are anticipating a 30-50% drop in the near future, and there isn't much we can do about it," says Alex Chan, chief of the retail division of a regional chain of jewelry stores. "We have our staff cleaning the floors and the show windows every hour." Its employees wear gloves and sterilize jewelry before customers try pieces on, but the company has stopped short of instructing staff to wear face masks. "I think wearing masks will scare off customers," Chan says.

Economists say losses will be contained if the SARS outbreak—which is not yet widespread enough to be considered an epidemic—burns out. The prognosis is unclear. Thanks to swift and pervasive e-mail communication and unprecedented collaboration among scientists and doctors worldwide, rapid progress is being made on the research front. Last week, pathologists at the University of Hong Kong scored a breakthrough when they announced the probable SARS culprit was a mutated coronavirus. Their finding, which controverted earlier research that pointed at the paramyxoviridae family of viruses, was confirmed by the U.S. Centers for Disease Control and Prevention in Atlanta. Still, it's possible that paramyxoviridae, which causes mumps and measles, might play a role in the disease. In the meantime, the identification of the coronavirus has made it possible to come up with diagnostic tests for the disease.

There is other good news. The coronavirus currently is not believed to be airborne, meaning that it can't float through the air like a mushroom spore. Instead, it can only be passed by direct contact with an infected person or with an object they have touched. And, while the number of cases is rising, the toll is not increasing exponentially. Steps such as those taken in Hong Kong and Singapore can strangle the outbreak before it reaches epidemic proportions. "We've come a tremendous distance since three weeks ago," says Chung, the dean of the medical faculty at the Chinese University of Hong Kong. "We know a lot more about the disease, the diagnosis and treatment." There is still no sure cure—antibiotics are useless against viruses—but patients in Hong Kong are responding to broad-spectrum, antiviral drugs combined with doses of steroids to reduce inflammation. "Patients are getting better," says Chung. "The majority are now recovering." But Chung quickly adds that the coronavirus has already spread through the Hong Kong community and is making inroads elsewhere. "I think this disease is going to be with us for a long time," he says. The world now has a new viral enemy to contend with, and its deadly capacity is only beginning to be understood.

Reported by Ilya Garger, Neil Gough, Carmen Lee and Bryan Walsh/Hong Kong, Kay Johnson/Hanoi, Daffyd Roderick/Toronto and Genevieve Wilkinson/Singapore

<a href=www.slovensko.com>Slovenko.com Mon 31-Mar  [RSI] Officials of the National respiratory Centre in Bratislava informed that there are no cases of Severe Acute Respiratory Syndrome or SARS registered in Slovakia so far. The disease is characterised by a high fever and the symptoms are very similar to that of flu. It first appeared in South East Asia earlier this year and infected over 1300 people. 50 of them died. The Slovak Foreign Ministry has asked citizens to avoid countries in East and Southeast Asia, especially China, Hong-Kong, Vietnam, Taiwan, and Singapore. It also called on citizens to rethink a trip to Canada, where some cases of SARS were registered last week.

<a href=iol.co.za>IOL March 31 2003 at 03:31PM By Tan Ee Lyn

Hong Kong - Doctors in Hong Kong have successfully treated some of the people suffering from the killer pneumonia virus sweeping across the continent by using serum taken from patients who have recovered, a health expert said on Monday.

This means that victims have been able to produce antibodies - found in serum - to fight the killer virus. Some experts had earlier feared that this would not happen as the body could not easily develop antibodies to fight a new virus.

The disease, known as severe acute respiratory syndrome (SARS), began in southern China in November and later spread to Hong Kong, Singapore, Vietnam, Canada, Germany, the United States, Germany and Taiwan.

Experts have said it could have originated from animalsIt has killed 61 people and infected over 1 600 worldwide.

"Facts have proven that in at least 20 of our patients who went through very smooth recovery, their serum has been used to treat very severe sufferers and that has been very successful," said Leung Ping-chung, a professor and surgeon at the Prince of Wales Hospital where the outbreak of the pneumonia virus in Hong Kong was first concentrated.

"The serum of at least 20 patients has been life-saving in the past two weeks for those who were severely ill."

Leung said the presence of antibodies means those who have recovered would have developed some level of immunity against the virus.

Doctors have identified the virus as a new strain from the family of coronaviruses, which causes the common cold. But they are trying to further understand its behaviour and characteristics.

'It will be very stupid not to protect yourself'Experts believe it could have originated from animals, adding that it could take years to develop a cure and a vaccine.

Apart from using serum from recovered patients, doctors in Hong Kong have been using a cocktail of anti-virals and steroids, which they say have been effective for many patients.

Although previous evidence has pointed to a transmission by droplets - through coughing and sneezing - a new wave of infections involving people living in a single residential block has led experts to question if the virus may be airborne or waterborne.

Of the over 600 people infected in Hong Kong, 213 are from a housing estate and of these, 107 are from a single block.

"The drainage may not be good and it may have regurgitated some of the contaminated sputum," Leung said.

"We are now examining all possible angles, to see if it is airborne or in the building's water mains," a government spokesperson said.

But whether the virus is spread through droplets or airborne, Leung and other experts in the territory have strongly recommended the use of protection masks, even though no one can ever guarantee they are foolproof.

"Even droplets can pierce through masks. Nothing can ever be foolproof. But given the situation, it will be very stupid not to protect yourself," he said.

Millions of people in Hong Kong are now using masks in public transport and congested areas to protect themselves.